| FT | Avispa Fukuoka | 1-1 (1-0) | Fagiano Okayama FC | ||
| FT | Kashima Antlers | 1-0 (0-0) | Nagoya Grampus | ||
| FT | Kyoto Sanga FC | 2-1 (1-0) | Yokohama FC | ||
| FT | Machida Zelvia | 0-1 (0-0) | Shonan Bellmare | ||
| FT | Tokyo Verdy | 1-0 (1-0) | Cerezo Osaka | ||
| FT | FC Tokyo | 3-0 (0-0) | Gamba Osaka | ||
| FT | Urawa Red Diamonds | 1-0 (0-0) | Sanfrecce Hiroshima |
| FT | Macarthur FC | 1-2 (0-2) | Melbourne Victory |
| FT | CD Nublense | 2-0 (0-0) | La Serena | ||
| FT | Union La Calera | 1-0 (1-0) | Audax Italiano |
| FT | Atletico Tembetary | 1-1 (0-0) | 2 de Mayo |
| FT | Famalicao | 1-1 (1-0) | Braga |
| FT | Beerschot | 2-0 (2-0) | Kortrijk |
| FT | Stoke City | 0-2 (0-1) | Sheffield United |
| FT | RKC Waalwijk | 0-4 (0-3) | FC Utrecht | ||
| FT | Feyenoord | 4-0 (3-0) | PEC Zwolle |
| FT | Bray Wanderers | 4-2 (2-0) | Kerry FC | ||
| FT | Cobh Ramblers | 3-1 (2-0) | Finn Harps | ||
| FT | Treaty United | 1-0 (0-0) | Athlone Town | ||
| FT | Wexford FC | 0-1 (0-0) | UCD |
| FT | Bohemian FC | 2-1 (0-1) | St. Patrick's Athletic | ||
| FT | Galway United FC | 2-1 (0-1) | Drogheda United | ||
| FT | Shamrock Rovers | 2-2 (1-0) | Shelbourne | ||
| FT | Waterford FC | 2-1 (1-0) | Derry City |
| FT | Paris St-Germain | 1-3 (1-1) | Nice |
| FT | Frosinone | 2-2 (2-1) | Spezia | ||
| FT | Bari | 1-2 (1-2) | Modena | ||
| FT | Brescia | 1-2 (0-1) | Pisa | ||
| FT | Carrarese | 1-0 (1-0) | Sampdoria | ||
| FT | Reggiana | 2-1 (0-0) | Cittadella | ||
| FT | Salernitana | 3-1 (0-0) | Cosenza | ||
| FT | Cremonese | 4-2 (1-1) | Mantova |
| FT | VfB Stuttgart | 0-1 (0-0) | FC Heidenheim |
| FT | Puszcza Niepolomice | 4-5 (1-2) | Pogon Szczecin |
| FT | FC Unirea Slobozia | 1-1 (1-0) | CSM Politehnica Iasi | ||
| FT | Sepsi OSK | 0-3 (0-2) | Otelul Galati |
| FT | Al Ahly SC | 1-1 (1-0) | Mamelodi Sundowns FC | ||
| FT | Pyramids FC | 3-2 (1-1) | Orlando Pirates |
| FT | Annecy FC | 2-0 (0-0) | AC Ajaccio | ||
| FT | Guingamp | 2-1 (1-0) | Martigues | ||
| FT | Laval | 1-0 (0-0) | Amiens | ||
| FT | Red Star | 1-1 (1-0) | Clermont Foot | ||
| FT | SC Bastia | 2-3 (1-1) | Grenoble | ||
| FT | Troyes | 1-0 (1-0) | Dunkerque |
| FT | Nyiregyhaza Spartacus FC | 1-0 (0-0) | Debreceni VSC |
| FT | BATE Borisov | 2-0 (1-0) | FK Slutsk | ||
| FT | Slavia Mozyr | 1-1 (0-0) | Arsenal Dzerzhinsk |
| FT | Hartberg | 1-1 (1-1) | Grazer AK |
| FT | Slavia Sofia | 3-2 (3-2) | Hebar | ||
| FT | PFC Lokomotiv Sofia 1929 | 3-0 (3-0) | Krumovgrad |
| FT | Randers FC | 0-0 (0-0) | Broendby IF |
| FT | Zalgiris Vilnius | 2-3 (2-1) | FK Panevezys |
| FT | ASO Chlef | 1-1 (0-0) | US Biskra | ||
| FT | MC Oran | 1-0 (0-0) | Olympique Akbou |
| FT | Besiktas | 5-1 (1-1) | Hatayspor |
| FT | Oliveirense | 2-0 (1-0) | Academico Viseu | ||
| FT | Pacos de Ferreira | 2-3 (1-1) | Uniao de Leiria |
| FT | Al Hilal | 7-0 (3-0) | Gwangju FC |
| FT | Greuther Fuerth | 0-1 (0-0) | Ulm | ||
| FT | Hertha Berlin | 1-1 (1-1) | Magdeburg |
| FT | Dynamo Makhachkala | 2-3 (1-2) | FC Krasnodar |
| FT | AEL Limassol | 1-3 (1-2) | Anorthosis |
| FT | Trencin | 2-2 (0-2) | Dukla Banska Bystrica |
| FT | FK Liepaja | 2-2 (2-0) | SK Super Nova | ||
| FT | BFC Daugavpils | 2-0 (2-0) | FS Metta/LU |
| FT | Kolkheti-1913 Poti | 2-1 (1-0) | FC Samgurali Tskhaltubo | ||
| FT | Dinamo Tbilisi | 1-1 (0-0) | Dinamo Batumi |
| FT | Inhulets Petrove | 0-1 (0-1) | FC Oleksandriya | ||
| FT | Zorya | 2-1 (1-0) | Liviy Bereh |
| FT | Turan Tovuz | 1-1 (0-0) | Shamakhi FK |
| FT | Beijing Guoan | 1-0 (1-0) | Henan FC | ||
| FT | Yunnan Yukun | 2-3 (0-1) | Shanghai Port |
| FT | Vancouver Whitecaps | 2-0 (1-0) | Inter Miami CF |
| FT | Universidad Catolica | 3-1 (1-1) | Defensa y Justicia |
| FT | Deportes Iquique | 2-2 (1-1) | Cienciano |
| FT | Palestino | 2-1 (1-0) | Cruzeiro |
| FT | Bolivar | 2-3 (0-2) | Palmeiras | ||
| FT | Cerro Porteno | 2-2 (2-1) | Sporting Cristal |
| FT | Bahia | 1-0 (0-0) | Atletico Nacional |
| FT | Godoy Cruz | 2-2 (0-1) | Gremio |
| FT | Corinthians | 1-0 (0-0) | Racing |
| FT | Central Cordoba de Santiago | 2-1 (2-1) | Deportivo Tachira |
