| FT | Envigado | 2-2 (1-0) | Junior FC | ||
| FT | Santa Fe | 2-0 (1-0) | Bucaramanga | ||
| FT | Independiente Medellin | 1-0 (1-0) | CD Jaguares | ||
| FT | Deportivo Pasto | 0-1 (0-0) | Tolima |
| FT | CD Guadalajara | 2-2 (1-1) | Necaxa | ||
| FT | CF America | 2-1 (1-1) | Queretaro FC | ||
| FT | Toluca | 1-0 (0-0) | Club Universidad Nacional | ||
| FT | Santos Laguna | 1-0 (0-0) | Monterrey |
| FT | San Lorenzo | 2-1 (2-1) | Arsenal Sarandi | ||
| FT | Defensa y Justicia | 3-2 (2-1) | Huracan | ||
| FT | Boca Juniors | 2-2 (1-1) | Gimnasia LP | ||
| FT | Estudiantes | 2-1 (0-0) | River Plate |
| FT | Luqueno | 0-3 (0-3) | Nacional | ||
| FT | Olimpia | 0-0 (0-0) | Guairena |
| FT | Flamengo | 2-1 (1-1) | Corinthians | ||
| FT | Vasco da Gama | 0-2 (0-1) | Internacional | ||
| FT | Athletico Paranaense | 2-1 (0-0) | Atletico GO | ||
| FT | Palmeiras | 3-0 (3-0) | Fortaleza | ||
| FT | Gremio | 1-2 (1-0) | Sao Paulo |
| FT | Everton CD | 1-0 (1-0) | Huachipato | ||
| FT | Universidad de Concepcion | 1-2 (1-0) | Universidad Catolica | ||
| FT | Deportes Iquique | 2-0 (0-0) | Santiago Wanderers | ||
| FT | La Serena | 0-2 (0-0) | Audax Italiano | ||
| FT | O'Higgins | 1-1 (0-0) | Colo Colo | ||
| FT | Palestino | 2-2 (1-1) | Coquimbo Unido |
| FT | Portimonense | 4-1 (2-1) | Gil Vicente | ||
| FT | Santa Clara | 0-1 (0-1) | Braga | ||
| FT | Moreirense | 1-1 (1-1) | Benfica |
| FT | Mallorca | 1-2 (0-1) | Espanyol | ||
| FT | Almeria | 3-1 (1-0) | Las Palmas | ||
| FT | Alcorcon | 1-0 (1-0) | Logrones | ||
| FT | Leganes | 3-1 (2-0) | Albacete | ||
| FT | Sporting Gijon | 1-0 (0-0) | Malaga |
| FT | Getafe | 0-1 (0-1) | Real Sociedad | ||
| FT | Real Madrid | 2-0 (2-0) | Valencia | ||
| FT | Levante | 0-1 (0-0) | Osasuna | ||
| FT | Villarreal | 1-2 (0-1) | Real Betis |
| FT | Monaco | 2-2 (0-1) | Lorient | ||
| FT | Angers | 1-3 (1-2) | Nantes | ||
| FT | Dijon | 0-2 (0-0) | Nîmes | ||
| FT | Metz | 1-2 (1-1) | Strasbourg | ||
| FT | Rennes | 0-2 (0-1) | St-Etienne | ||
| FT | Lille | 0-0 (0-0) | Brest | ||
| FT | Bordeaux | 0-0 (0-0) | Marseille |
| FT | Roma | 3-0 (2-0) | Udinese | ||
| FT | Cagliari | 0-1 (0-0) | Atalanta | ||
| FT | Sampdoria | 2-1 (1-1) | Fiorentina | ||
| FT | Crotone | 1-2 (1-1) | Sassuolo | ||
| FT | Inter Milan | 3-1 (2-0) | Lazio |
| FT | Standard Liege | 1-1 (1-1) | Royal Antwerp | ||
| FT | Beerschot | 1-2 (0-0) | KV Mechelen | ||
| FT | Cercle Bruges | 0-0 (0-0) | Anderlecht |
| FT | Southampton | 1-2 (1-0) | Wolverhampton Wanderers | ||
| FT | West Bromwich Albion | 1-1 (1-1) | Manchester United | ||
| FT | Arsenal | 4-2 (3-0) | Leeds United | ||
| FT | Everton | 0-2 (0-0) | Fulham |
| FT | Union St.Gilloise | 3-1 (1-1) | Club Brugge NXT | ||
| FT | K. Lierse SK | 1-1 (1-0) | Deinze |
| FT | AaB | 0-0 (0-0) | Randers FC | ||
| FT | Vejle Boldklub | 2-2 (1-0) | FC Nordsjaelland | ||
| FT | Lyngby | 0-4 (0-2) | Broendby IF | ||
| FT | FC Midtjylland | 1-0 (0-0) | AC Horsens | ||
| FT | OB | 0-0 (0-0) | AGF |
| FT | Chabab Mohammedia | 0-1 (0-1) | MCO Oujda | ||
| FT | Olympic Club de Safi | 1-1 (1-1) | MAS Fes | ||
| FT | Youssoufia Berrechid | 1-0 (1-0) | RSB Berkane |
| FT | Gzira United | 1-0 (0-0) | Lija | ||
| FT | Sirens FC | 0-1 (0-0) | Valletta | ||
| FT | Gudja United | 1-1 (0-0) | Sliema Wanderers |
| FT | CSM Politehnica Iasi | 2-3 (1-3) | Astra Giurgiu | ||
| FT | FC Academica Clinceni | 0-0 (0-0) | Universitatea Craiova | ||
| FT | Hermannstadt | 1-0 (1-0) | FCSB |
| FT | Aris Thessaloniki FC | 0-0 (0-0) | Panetolikos | ||
| FT | OFI Crete | 1-2 (0-2) | NFC Volos | ||
| FT | Panathinaikos | 2-1 (1-0) | Olympiacos |
| FT | Tabor | 1-1 (0-1) | Aluminij | ||
| FT | NK Celje | 0-2 (0-1) | Domzale | ||
| FT | Olimpija Ljubljana | 2-0 (0-0) | Mura |
| FT | Virtus Entella | 2-3 (1-2) | Frosinone | ||
| FT | Reggiana | 1-0 (0-0) | Ascoli Calcio 1898 FC | ||
| FT | Brescia | 1-0 (1-0) | Chievo Verona |
| FT | Mafra | 1-1 (0-1) | Leixoes | ||
| FT | Chaves | 0-0 (0-0) | Benfica B | ||
| FT | FC Porto B | 1-2 (1-1) | Oliveirense | ||
| FT | Casa Pia AC | 0-1 (0-0) | Feirense |
| FT | Eintracht Frankfurt | 2-0 (0-0) | FC Koeln | ||
| FT | VFL Wolfsburg | 0-0 (0-0) | Borussia Moenchengladbach |
| FT | Hapoel Hadera | 1-0 (1-0) | Maccabi Petach Tikva |
| FT | Wisla Plock | 1-0 (0-0) | Lech Poznan | ||
| FT | Jagiellonia Bialystok | 1-1 (1-1) | Legia Warszawa |
| FT | Karmiotissa Pano Polemidion | 0-3 (0-1) | Olympiakos Nicosia | ||
| FT | APOEL Nicosia | 3-1 (2-0) | Nea Salamis |
| FT | Austria Wien | 0-1 (0-1) | Hartberg | ||
| FT | Ried | 1-1 (1-0) | SKN St. Poelten | ||
| FT | LASK | 2-0 (1-0) | Sturm Graz |
| FT | Mezokovesd SE | 2-2 (0-1) | Ferencvarosi TC | ||
| FT | Fehervar FC | 1-2 (1-0) | MTK Budapest |
| FT | AZ Alkmaar | 3-1 (1-0) | SC Heerenveen | ||
| FT | FC Utrecht | 3-1 (0-0) | VVV-Venlo | ||
| FT | Feyenoord | 5-0 (1-0) | Willem II | ||
| FT | Vitesse Arnhem | 0-2 (0-1) | FC Twente |
| FT | FC Lucerne | 4-0 (2-0) | FC Vaduz | ||
| FT | FC Zürich | 2-0 (1-0) | FC Bâle | ||
| FT | Lugano | 1-3 (0-3) | Young Boys |
| FT | FC Kolos Kovalivka | 0-0 (0-0) | Shakhtar Donetsk | ||
| FT | Mariupol | 0-1 (0-1) | FC Oleksandriya | ||
| FT | Rukh Lviv | 1-1 (1-0) | Vorskla | ||
| FT | SC Dnipro-1 | 2-0 (2-0) | Inhulets Petrove |
| FT | Banik Ostrava | 2-1 (2-1) | Jablonec | ||
| FT | Bohemians 1905 | 0-0 (0-0) | Sigma Olomouc | ||
| FT | Mlada Boleslav | 2-2 (1-1) | Viktoria Plzen | ||
| FT | Slovan Liberec | 0-0 (0-0) | SK Dynamo Ceske Budejovice | ||
| FT | Sparta Prague | 4-3 (3-2) | Karvina |
| FT | CSKA 1948 | 2-1 (1-0) | FC Tsarsko Selo Sofia 2015 | ||
| FT | Levski Sofia | 2-0 (1-0) | Montana |
| FT | Dinamo Moscow | 2-4 (1-2) | PFC Sochi | ||
| FT | Lokomotiv Moscow | 0-4 (0-1) | Lokomotivi Tbilisi | ||
| FT | Haecken | 3-1 (1-1) | Oergryte FF | ||
| FT | Kalmar FF | 0-2 (0-1) | Landskrona BoIS | ||
| FT | BATE Borisov | 1-1 (0-1) | FC Ufa | ||
| FT | Dinamo Moscow | 2-1 (1-0) | Ordabasy Shymkent | ||
| FT | Lokomotiv Moscow | 2-1 (2-0) | FC Rostov |
| FT | Rijeka | 1-1 (1-1) | NK Istra 1961 |
| FT | FK Pohronie | 1-1 (1-1) | Zemplin Michalovce | ||
| FT | Trencin | 3-3 (2-0) | DAC 1904 Dunajska Streda |
| FT | Damac FC | 1-0 (1-0) | Al Hilal |
| FT | St Omer | 0-1 (0-0) | GFC Ajaccio | ||
| FT | AS Steenvoorde | 2-4 (1-1) | Beauvais | ||
| Pen. | Amneville | 0-0(0-0) | Prix-les-Mezieres* | ||
| Pen. | Elan de Gorges | 0-0(0-0) | Sable FC* | ||
| FT | Fabregues | 4-1 (1-0) | Castelnau Le Cres | ||
| Pen. | Feurs | 0-0(0-0) | Le Puy* | ||
| FT | GFA Rumilly Vallieres | 5-1 (3-1) | St Priest | ||
| FT | Gonfreville | 0-2 (0-0) | Voltigeurs de Chateaubriant | ||
| FT | La Saint Colomban Locmine | 0-1 (0-0) | Guichen | ||
| Pen. | *Loon Plage | 1-1(1-1) | Arras | ||
| FT | Louhans Cuiseaux | 0-1 (0-1) | FC Fleury 91 | ||
| FT | Merignac Arlac | 1-4 (1-1) | Stade Poitevin | ||
| Pen. | *OM Aire sur La Lys | 0-0(0-0) | Amiens AC | ||
| FT | Racing Besancon | 0-1 (0-1) | UF Maconnais | ||
| FT | St Brice | 2-0 (0-0) | Drancy | ||
| FT | St Meziery | 0-5 (0-3) | Sedan | ||
| FT | US Montagnarde | 1-0 (1-0) | Dinan-Lehon | ||
| Pen. | Athletico Marseille | 0-0(0-0) | Aubagne* | ||
| Pen. | *Chamalieres | 1-1(1-1) | Andrezieux Boutheon | ||
| FT | FC Soleil Bischheim | 0-1 (0-1) | Schiltigheim | ||
| Pen. | FCSR Haguenau | 2-2(2-2) | Saint Louis Neuweg* | ||
| FT | Lege Cap Ferret | 1-0 (1-0) | Aviron Bayonnais FC | ||
| FT | St Clement Montferrier | 0-2 (0-0) | Canet Roussillon | ||
| FT | St Liguaire Niort | 0-2 (0-1) | Olympique Ales |
| FT | FK Qabala | 2-0 (0-0) | Shamakhi FK | ||
| FT | Zira | 2-2 (0-1) | Sabah FK |
| FT | Konyaspor | 2-0 (0-0) | Denizlispor | ||
| FT | Galatasaray | 2-1 (1-0) | Kasimpasa | ||
| FT | Goztepe | 2-1 (1-0) | Istanbul Basaksehir | ||
| FT | Hatayspor | 0-0 (0-0) | Alanyaspor |
| FT | Brentford | 0-2 (0-1) | Barnsley |
| FT | Darmstadt | 1-0 (1-0) | Osnabrueck | ||
| FT | Nuernberg | 1-2 (0-1) | St. Pauli | ||
| FT | VFL Bochum | 2-0 (2-0) | Eintracht Braunschweig |
| FT | St. Johnstone | 1-2 (0-0) | Celtic |
| FT | Wellington Phoenix | 0-2 (0-1) | Central Coast Mariners | ||
| FT | Brisbane Roar FC | 0-0 (0-0) | Newcastle Jets |
